Literature Database Entry

lau2025using

Florian-Lennert Adrian Lau, Lara Josephine Prange, Regine Wendt, Sarah Scheer, Christian Hyttrek, Saswati Pal, Jorge Torres Gómez, Falko Dressler and Stefan Fischer, "Using Off-the-Shelf Biosensors to Implement Gateways for Alarm-System Nanonetworks," Elsevier Nano Communication Networks, vol. 45, pp. 100584, September 2025.

Abstract

DNA-based nanonetworks hold great promise for future biomedical applications, especially in the areas of early disease detection and targeted therapy. However, reliably transmitting information from the nanoscale to external monitoring systems remains a major challenge. This paper explores using commercially available continuous glucose monitoring (CGM) sensors as gateways between in vivo nanonetworks and external devices. We propose a novel architecture in which DNA-based nanosensors release glucose as a signaling molecule when disease-relevant biomarkers are detected. CGM systems can detect these glucose surges, enabling real-time external communication. After analyzing various biosensor types, we found that CGM sensors are the most viable option due to their widespread availability, bio-compatibility, and ability to measure biochemical signals. We present several architectural alternatives, calculate the required signal strength for reliable detection, and discuss potential experimental validation strategies. Our findings highlight a feasible and practical pathway toward integrating nanoscale diagnostics with existing biosensing technologies.

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Florian-Lennert Adrian Lau
Lara Josephine Prange
Regine Wendt
Sarah Scheer
Christian Hyttrek
Saswati Pal
Jorge Torres Gómez
Falko Dressler
Stefan Fischer

BibTeX reference

@article{lau2025using,
    author = {Lau, Florian-Lennert Adrian and Prange, Lara Josephine and Wendt, Regine and Scheer, Sarah and Hyttrek, Christian and Pal, Saswati and Torres G{\'{o}}mez, Jorge and Dressler, Falko and Fischer, Stefan},
    doi = {10.1016/j.nancom.2025.100584},
    title = {{Using Off-the-Shelf Biosensors to Implement Gateways for Alarm-System Nanonetworks}},
    pages = {100584},
    journal = {Elsevier Nano Communication Networks},
    issn = {1878-7789},
    publisher = {Elsevier},
    month = {9},
    volume = {45},
    year = {2025},
   }
   
   

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